2686 Brevetoxin Brevetoxins are cyclic polyether compounds produced naturally by a species of dinoflagellates (Karenia brevis). They are neurotoxins that bind to voltage-gated sodium channels in nerve cells, leading to disruption of normal neurological processes and causing the illness clinically described as neurotoxic shellfish poisoning. (L1112) 98112-41-5 105135 C49H68O14 867.0723 White powder. Injection (sting/bite) (L1815) Brevetoxins are neurotoxins that bind to voltage-gated sodium channels in nerve cells, leading to disruption of normal neurological processes. (L1112) No indication of carcinogenicity to humans (not listed by IARC). Brevetoxins are cyclic polyether compounds produced naturally by a species of dinoflagellates (Karenia brevis). (L1112) Brevetoxins are neurotoxins that cause the illness clinically described as neurotoxic shellfish poisoning. (L1112) Brevetoxins are neurotoxins that cause the illness clinically described as neurotoxic shellfish poisoning. Symptoms include vomiting and nausea and a variety of neurologic symptoms such as slurred speech. (L1112) 2009-07-06T21:35:50Z 2014-12-24T20:25:48Z C16839 Brevetoxin true [H]\C1=C([H])\[C@@]2([H])O[C@@]3([H])C[C@@]4([H])O[C@]([H])(CC(=C)C=O)C[C@]([H])(O)[C@]4(C)O[C@]3([H])C[C@]2([H])O[C@]2([H])C[C@]3(C)O[C@]4(C)CC[C@]5([H])O[C@]6([H])C[C@]7(C)O[C@]8([H])C(C)=CC(=O)O[C@@]8([H])C[C@@]7([H])O[C@@]6([H])C[C@@]([H])(C)[C@@]5([H])O[C@@]4([H])C[C@@]3([H])O[C@@]2([H])C1 C49H68O14 InChI=1S/C49H68O14/c1-24(23-50)13-27-16-38(51)49(7)42(53-27)18-33-34(61-49)17-32-28(54-33)9-8-10-29-36(56-32)22-48(6)41(57-29)20-40-46(4,63-48)12-11-30-44(60-40)25(2)14-31-37(55-30)21-47(5)39(58-31)19-35-45(62-47)26(3)15-43(52)59-35/h8-9,15,23,25,27-42,44-45,51H,1,10-14,16-22H2,2-7H3/b9-8-/t25-,27-,28-,29+,30+,31+,32+,33+,34-,35+,36-,37-,38+,39-,40+,41-,42-,44-,45-,46-,47+,48+,49+/m1/s1 InChIKey=WTXGTTBOKVQBGS-ZOTXBKINSA-N 881.0558 880.460906884 Exogenous Solid CHEMBL1077122 24684127